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Psychiatry · Organic mental disorders: alexia without agraphia
Sample itemA 70-year-old man after a left posterior cerebral artery infarct has a right homonymous hemianopia. He can write sentences and speak normally, but cannot read what he has written. Which disconnection syndrome is this?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Pure alexia from a left occipital and splenial lesion
In alexia without agraphia the left visual cortex is destroyed and the splenium of the corpus callosum is damaged, so visual input from the intact right occipital cortex cannot reach the left-hemisphere language areas. Writing and speech remain intact.
Option by option
A. Gerstmann syndrome from a parietal lesion
Gerstmann syndrome includes agraphia, so writing would be impaired.
B. Broca aphasia from an inferior frontal lesion
Broca aphasia affects speech production and is not a reading disorder.
C. Pure alexia from a left occipital and splenial lesion (correct)
Correct. Occipital cortex plus splenial damage disconnects vision from language.
D. Alexia with agraphia from an angular gyrus lesion
Alexia with agraphia affects both reading and writing, from an angular gyrus lesion.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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