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Radiology · Radiation safety and radiobiology: latent period of acute radiation syndrome
Sample itemA worker exposed to a high whole-body dose has nausea and vomiting for the first day, then feels well for about two weeks before fever, infection and bleeding appear. What is the symptom-free interval called?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Latent period
Acute radiation syndrome has four phases: prodromal, latent, manifest illness and recovery or death. During the latent period the patient seems well while marrow stem cells are depleted, and it is shorter with higher doses.
Option by option
A. Manifest illness stage
The manifest illness stage is when infection and bleeding occur.
B. Prodromal stage
The prodromal stage is the initial nausea and vomiting.
C. Recovery stage
The recovery stage follows the manifest illness in survivors.
D. Latent period (correct)
Correct. The apparently well interval between the prodrome and the manifest illness is the latent period.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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