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Radiology · Chest and cardiac imaging: reverse halo sign
Sample itemA patient with subacute cough and fever has not responded to a course of antibiotics. CT shows a focus of central ground-glass attenuation surrounded by a ring of denser consolidation. Which diagnosis is most likely?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Cryptogenic organising pneumonia
A central ground-glass area rimmed by consolidation is the reverse halo, or atoll, sign, most characteristic of organising pneumonia. It also occurs in pulmonary infarcts and some fungal infections.
Option by option
A. Pulmonary alveolar proteinosis
Alveolar proteinosis gives geographic ground glass with septal thickening, the crazy-paving pattern.
B. Cryptogenic organising pneumonia (correct)
Correct. This is a recognised sign of organising pneumonia in a patient unresponsive to antibiotics.
C. Usual interstitial pneumonia
UIP gives basal subpleural reticulation and honeycombing, not a ring of consolidation.
D. Hypersensitivity pneumonitis
Hypersensitivity pneumonitis gives centrilobular nodules, mosaic attenuation and air trapping.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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