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Radiology · Neuroimaging: artery of Percheron infarct
Sample itemA patient wakes up drowsy with a vertical gaze palsy and memory loss. MRI shows bilateral paramedian thalamic diffusion restriction with a midbrain extension. What is the most likely cause?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Occlusion of the artery of Percheron
The artery of Percheron is a single trunk from a posterior cerebral artery that supplies both paramedian thalami and the rostral midbrain. Its occlusion causes bilateral infarcts with hypersomnolence, vertical gaze palsy and amnesia.
Option by option
A. Occlusion of the artery of Percheron (correct)
Correct. Bilateral paramedian thalamic infarcts with midbrain involvement indicate a Percheron occlusion.
B. Deep cerebral venous thrombosis
Deep venous thrombosis causes bilateral thalamic oedema, often with haemorrhage and venous clot on venography.
C. Bilateral lenticulostriate occlusion
Lenticulostriate occlusion causes basal ganglia lacunes, not paramedian thalamic infarcts.
D. Wernicke encephalopathy
Wernicke encephalopathy follows thiamine deficiency and affects the mamillary bodies and periaqueductal region.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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