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Radiology · Neuroimaging: intracranial hypotension
Sample itemAfter an epidural procedure, a woman has a headache that is worse upright and relieved lying flat. Post-gadolinium MRI shows diffuse smooth pachymeningeal enhancement, downward sagging of the brainstem and engorged venous sinuses. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Intracranial hypotension from a CSF leak
Loss of CSF volume causes the brain to sag, the dural veins to engorge and the pachymeninges to enhance diffusely. Postural headache and a recent dural puncture clinch the diagnosis, and an epidural blood patch is the treatment.
Option by option
A. Idiopathic intracranial hypertension
IIH shows an empty sella, flattened globes and distended optic sheaths, with headache worse lying down.
B. Meningeal carcinomatosis
Carcinomatosis shows nodular leptomeningeal enhancement rather than smooth dural thickening.
C. Tuberculous meningitis
Tuberculous meningitis enhances the basal leptomeninges with hydrocephalus and infarcts.
D. Intracranial hypotension from a CSF leak (correct)
Correct. Diffuse smooth dural enhancement, brain sagging and venous engorgement with postural headache fit a CSF leak.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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