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Radiology · Musculoskeletal imaging: chondroblastoma
Sample itemA 15-year-old with an open growth plate has months of knee pain. A radiograph shows a well-defined lytic lesion in the proximal tibial epiphysis with a thin sclerotic rim and fine internal calcification. Which tumour is most likely?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Chondroblastoma
Chondroblastoma is a cartilage tumour that arises in the epiphysis of a skeletally immature patient, often with a sclerotic rim and chondroid calcification. Giant cell tumour is also epiphyseal but typically appears after the physis has closed.
Option by option
A. Chondroblastoma (correct)
Correct. An epiphyseal lytic lesion with a sclerotic rim and calcification in an adolescent with an open physis is chondroblastoma.
B. Non-ossifying fibroma
Non-ossifying fibroma is a metaphyseal cortical-based lesion, not an epiphyseal one.
C. Giant cell tumour
Giant cell tumour is epiphyseal and lytic, but it typically occurs after physeal closure and lacks matrix calcification.
D. Enchondroma
Enchondroma is a medullary lesion of the metaphysis or diaphysis, usually in the small bones of the hand.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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