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Radiology · Musculoskeletal imaging: haemophilic arthropathy
Sample itemA 12-year-old boy with prolonged bleeding after dental extraction has recurrent bloody knee effusions. Radiographs show a widened intercondylar notch, a squared inferior patella, enlarged epiphyses and subchondral cysts. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Haemophilic arthropathy
Repeated haemarthrosis causes synovial hyperaemia and haemosiderin deposition, leading to epiphyseal overgrowth, a widened intercondylar notch, a squared patella and subchondral cysts. A bleeding history and bloody aspirates separate it from juvenile arthritis, which shows similar overgrowth.
Option by option
A. Tuberculous arthritis
Tuberculous arthritis causes the Phemister triad of osteopenia, peripheral erosions and narrowing, with a late-appearing joint space loss.
B. Haemophilic arthropathy (correct)
Correct. A bleeding diathesis with bloody effusions and epiphyseal overgrowth with a widened notch indicates haemophilic arthropathy.
C. Juvenile idiopathic arthritis
Juvenile idiopathic arthritis shows similar overgrowth but with non-bloody synovitis and no bleeding history.
D. Pigmented villonodular synovitis
Pigmented villonodular synovitis is usually monoarticular in adults, with synovial masses and erosions, and normal bone density.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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