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Dermatology · Viral infections: postherpetic neuralgia
Sample itemA 70-year-old has burning pain persisting in a thoracic dermatome 3 months after healed herpes zoster. Which drug is a first-line option?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Gabapentin or pregabalin
Postherpetic neuralgia is neuropathic pain that persists after zoster. First-line agents include gabapentinoids, tricyclic antidepressants and topical lidocaine.
Option by option
A. Topical corticosteroid
Topical steroids do not help neuropathic pain.
B. Paracetamol alone
Paracetamol has poor efficacy in neuropathic pain.
C. Gabapentin or pregabalin (correct)
Correct. Gabapentinoids treat neuropathic pain.
D. Oral acyclovir
Acyclovir treats active viral replication, which is finished here.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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