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Dermatology · Bacterial infections: recurrent furunculosis
Sample itemMultiple family members have recurrent furuncles with necrotising pneumonia in one case. Which staphylococcal toxin is implicated?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Panton-Valentine leukocidin
Panton-Valentine leukocidin lyses leukocytes and is associated with recurrent skin abscesses and severe necrotising pneumonia, especially in community-acquired MRSA. Management includes drainage and decolonisation with intranasal mupirocin and chlorhexidine washes.
Option by option
A. Enterotoxin B
Enterotoxin B causes food poisoning.
B. Panton-Valentine leukocidin (correct)
Correct. PVL is linked to recurrent abscesses and necrotising pneumonia.
C. Toxic shock syndrome toxin-1
TSST-1 causes toxic shock.
D. Exfoliative toxin A
Exfoliative toxin causes scalded skin syndrome.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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