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Dermatology · Skin tumours: infantile haemangioma
Sample itemA 3-month-old has a rapidly enlarging, bright red, raised vascular lesion over the face that is threatening the eye. Which drug is first line?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Oral propranolol
Infantile haemangiomas show GLUT1 positivity, a proliferative phase in the first year and slow involution afterwards. Propranolol is first-line for problematic lesions, and timolol gel is used for superficial ones.
Option by option
A. Oral propranolol (correct)
Correct. Propranolol is the standard systemic therapy.
B. Systemic steroids first line
Steroids are now second line.
C. Radiotherapy
Radiotherapy has unacceptable risks in infants.
D. Intralesional bleomycin
Bleomycin is not standard for haemangioma.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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