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Dermatology · Papulosquamous disorders: pityriasis rubra pilaris
Sample itemA man has orange-red scaly plaques with follicular papules and well-demarcated islands of normal skin, plus waxy orange palmoplantar keratoderma. Which is the most likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Pityriasis rubra pilaris
Pityriasis rubra pilaris presents with salmon-orange erythema, follicular hyperkeratosis, nutmeg-grater papules and islands of sparing. Acitretin and methotrexate are treatments, and biologics are used in refractory disease.
Option by option
A. Pityriasis rubra pilaris (correct)
Correct. Islands of sparing with orange palmoplantar keratoderma are characteristic.
B. Mycosis fungoides
Mycosis fungoides has patches and plaques with atypical lymphocytes.
C. Pityriasis versicolor
Pityriasis versicolor is a fine scaling pigment disorder.
D. Plaque psoriasis
Psoriasis has thick silvery scale and rarely islands of sparing.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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