Bullous disorders: pemphigus treatment: practice question

A Dermatology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Dermatology · Bullous disorders: pemphigus treatment

Sample item

Which drug is an established first-line adjuvant to systemic corticosteroids in moderate to severe pemphigus vulgaris?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Rituximab

Systemic corticosteroids remain the initial treatment, and rituximab (anti-CD20) improves remission rates and spares steroids. Azathioprine and mycophenolate are other adjuvants.

Option by option

  • A. Rituximab (correct)

    Correct. Rituximab is an effective first-line adjuvant.

  • B. Dapsone

    Dapsone is mainly used in dermatitis herpetiformis and linear IgA disease.

  • C. Doxycycline alone

    Doxycycline alone is not adequate for pemphigus vulgaris.

  • D. Griseofulvin

    Griseofulvin is an antifungal.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Dermatology questions

Questions about this Dermatology question

What is the answer to this Dermatology question?

The best answer is A, Rituximab. Systemic corticosteroids remain the initial treatment, and rituximab (anti-CD20) improves remission rates and spares steroids.

Why is "Dapsone" not the answer?

Dapsone is mainly used in dermatitis herpetiformis and linear IgA disease.

Why is "Doxycycline alone" not the answer?

Doxycycline alone is not adequate for pemphigus vulgaris.

Why is "Griseofulvin" not the answer?

Griseofulvin is an antifungal.

What concept does this question test?

It tests Bullous disorders: pemphigus treatment in Dermatology. Azathioprine and mycophenolate are other adjuvants.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Bullous disorders: pemphigus treatment?

Learn each condition by its primary lesion, site and signature sign. Then use the flashcards and the other Dermatology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.