Bullous disorders: linear IgA bullous disease: practice question

A Dermatology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Dermatology · Bullous disorders: linear IgA bullous disease

Sample item

A child has annular blisters forming a rosette, described as a string of pearls, with linear IgA at the basement membrane. Which drug is a well-known cause of the adult drug-induced form?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Vancomycin

Linear IgA bullous disease shows linear IgA along the basement membrane and can be drug induced, classically by vancomycin. Dapsone is first-line treatment.

Option by option

  • A. Amlodipine

    Amlodipine is not a typical trigger.

  • B. Metformin

    Metformin is not associated.

  • C. Vancomycin (correct)

    Correct. Vancomycin is the classic trigger.

  • D. Isoniazid

    Isoniazid is not a classic trigger.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Dermatology question

What is the answer to this Dermatology question?

The best answer is C, Vancomycin. Linear IgA bullous disease shows linear IgA along the basement membrane and can be drug induced, classically by vancomycin.

Why is "Amlodipine" not the answer?

Amlodipine is not a typical trigger.

Why is "Metformin" not the answer?

Metformin is not associated.

Why is "Isoniazid" not the answer?

Isoniazid is not a classic trigger.

What concept does this question test?

It tests Bullous disorders: linear IgA bullous disease in Dermatology. Dapsone is first-line treatment.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Bullous disorders: linear IgA bullous disease?

Learn each condition by its primary lesion, site and signature sign. Then use the flashcards and the other Dermatology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.