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Dermatology · Connective tissue disease: sarcoidosis of the skin
Sample itemA woman has violaceous, indurated plaques on the nose and cheeks with biopsy showing noncaseating naked epithelioid granulomas. Which name is given to this presentation?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Lupus pernio
Lupus pernio is a chronic sarcoidosis lesion of the nose, cheeks and ears, associated with chronic respiratory disease. Granulomas lack caseation and show few lymphocytes, described as naked granulomas.
Option by option
A. Rhinophyma
Rhinophyma is nasal enlargement from sebaceous hyperplasia in rosacea.
B. Lupus pernio (correct)
Correct. Violaceous plaques on the nose and cheeks in sarcoidosis are lupus pernio.
C. Lupus vulgaris
Lupus vulgaris is cutaneous tuberculosis with caseation.
D. Discoid lupus
Discoid lupus shows scarring and follicular plugging, without granulomas.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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