Papulosquamous disorders: psoriatic arthritis: practice question

A Dermatology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

Try it

Dermatology · Papulosquamous disorders: psoriatic arthritis

Sample item

A patient with psoriasis has sausage-shaped swelling of a toe and arthritis of the distal interphalangeal joints. Radiographs show a pencil-in-cup deformity. Which statement is correct?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. It is typically seronegative for rheumatoid factor

Psoriatic arthritis is a seronegative spondyloarthropathy with DIP involvement, dactylitis, asymmetric oligoarthritis and spondylitis, and nail disease is a risk marker. HLA-B27 is associated with axial disease.

Option by option

  • A. It affects only large joints

    It commonly affects small joints including the DIP joints.

  • B. It is strongly associated with HLA-DR4

    HLA-DR4 is linked to rheumatoid arthritis.

  • C. It always precedes the skin disease

    Skin disease usually precedes arthritis in most patients.

  • D. It is typically seronegative for rheumatoid factor (correct)

    Correct. Rheumatoid factor is typically negative.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Dermatology questions

Questions about this Dermatology question

What is the answer to this Dermatology question?

The best answer is D, It is typically seronegative for rheumatoid factor. Psoriatic arthritis is a seronegative spondyloarthropathy with DIP involvement, dactylitis, asymmetric oligoarthritis and spondylitis, and nail disease is a risk marker.

Why is "It affects only large joints" not the answer?

It commonly affects small joints including the DIP joints.

Why is "It is strongly associated with HLA-DR4" not the answer?

HLA-DR4 is linked to rheumatoid arthritis.

Why is "It always precedes the skin disease" not the answer?

Skin disease usually precedes arthritis in most patients.

What concept does this question test?

It tests Papulosquamous disorders: psoriatic arthritis in Dermatology. HLA-B27 is associated with axial disease.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Papulosquamous disorders: psoriatic arthritis?

Learn each condition by its primary lesion, site and signature sign. Then use the flashcards and the other Dermatology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.