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Dermatology · Leprosy: tuberculoid leprosy
Sample itemA man has a solitary, well-defined, dry, hairless, anaesthetic plaque with raised edges and a thickened nerve emerging from it. Slit skin smear is negative. Which is the most likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Tuberculoid leprosy
Tuberculoid leprosy shows few, sharply demarcated, anaesthetic lesions with early nerve thickening, a negative smear and a strongly positive lepromin test. The immune response is good but can damage nerves.
Option by option
A. Pityriasis alba
Pityriasis alba has normal sensation and no nerve thickening.
B. Tuberculoid leprosy (correct)
Correct. A solitary anaesthetic plaque with thickened nerve is typical.
C. Lepromatous leprosy
Lepromatous leprosy has many symmetric lesions with positive smears.
D. Granuloma annulare
Granuloma annulare has normal sensation and a ring of papules.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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