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Dermatology · STI: tertiary syphilis
Sample itemA patient has a painless, punched-out ulcer with a wash-leather base on the leg and a positive treponemal test, some years after untreated infection. What is the lesion?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Gumma
A gumma is a destructive granulomatous lesion of late benign tertiary syphilis that may affect skin, bone and viscera. Tertiary lesions have few spirochaetes and respond to penicillin.
Option by option
A. Gumma (correct)
Correct. A painless destructive granulomatous ulcer is a gumma.
B. Chancre
A chancre is the primary lesion at the inoculation site.
C. Chancroid
Chancroid is an acute painful ulcer.
D. Condyloma lata
Condylomata lata belong to the secondary stage.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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