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Dermatology · STI: lymphogranuloma venereum
Sample itemA man has tender unilateral inguinal lymph nodes separated by the inguinal ligament, forming a groove, several weeks after a painless transient genital papule. Which treatment is recommended?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Doxycycline 100 mg twice daily for 21 days
LGV is caused by Chlamydia trachomatis serovars L1 to L3 and shows the groove sign of Greenhouse. A 3-week course of doxycycline is used, and buboes may need aspiration.
Option by option
A. Doxycycline 100 mg twice daily for 21 days (correct)
Correct. Doxycycline for 21 days is the first-line therapy.
B. Benzathine penicillin single dose
Penicillin is used for syphilis.
C. Azithromycin 1 g single dose
Single dose azithromycin is used for uncomplicated chlamydia and chancroid.
D. Acyclovir for 7 days
Acyclovir is used for herpes.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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