STI: erythroplasia of Queyrat: practice question

A Dermatology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Dermatology · STI: erythroplasia of Queyrat

Sample item

An uncircumcised man has a persistent, well-demarcated, velvety red plaque on the glans penis unresponsive to antifungals. Biopsy shows full-thickness epidermal dysplasia. What is the diagnosis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Erythroplasia of Queyrat

Erythroplasia of Queyrat is squamous cell carcinoma in situ of the glans or prepuce, associated with HPV 16, and can progress to invasive carcinoma. Treatment options include topical 5-fluorouracil, imiquimod, laser or surgery.

Option by option

  • A. Balanitis xerotica obliterans

    Balanitis xerotica obliterans is lichen sclerosus with white sclerotic plaques.

  • B. Candidal balanitis

    Candidal balanitis responds to antifungals.

  • C. Zoon balanitis

    Zoon balanitis is a benign plasma cell balanitis with a plasma cell infiltrate.

  • D. Erythroplasia of Queyrat (correct)

    Correct. A persistent red velvety plaque with dysplasia is Queyrat erythroplasia.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Dermatology question

What is the answer to this Dermatology question?

The best answer is D, Erythroplasia of Queyrat. Erythroplasia of Queyrat is squamous cell carcinoma in situ of the glans or prepuce, associated with HPV 16, and can progress to invasive carcinoma.

Why is "Balanitis xerotica obliterans" not the answer?

Balanitis xerotica obliterans is lichen sclerosus with white sclerotic plaques.

Why is "Candidal balanitis" not the answer?

Candidal balanitis responds to antifungals.

Why is "Zoon balanitis" not the answer?

Zoon balanitis is a benign plasma cell balanitis with a plasma cell infiltrate.

What concept does this question test?

It tests STI: erythroplasia of Queyrat in Dermatology. Treatment options include topical 5-fluorouracil, imiquimod, laser or surgery.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study STI: erythroplasia of Queyrat?

Learn each condition by its primary lesion, site and signature sign. Then use the flashcards and the other Dermatology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.