Pigmentary disorders: vitiligo surgery: practice question

A Dermatology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Dermatology · Pigmentary disorders: vitiligo surgery

Sample item

Which condition is essential before offering melanocyte transplantation surgery for vitiligo?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Stable disease with no new lesions or Koebner phenomenon for at least 6 to 12 months

Surgical procedures such as suction blister grafting or cellular grafting succeed only in stable vitiligo, since active disease and Koebner phenomenon would depigment the graft and donor sites. Segmental vitiligo has the best outcomes.

Option by option

  • A. Stable disease with no new lesions or Koebner phenomenon for at least 6 to 12 months (correct)

    Correct. Stability for at least 6 to 12 months is required.

  • B. Recent use of oral steroid minipulse

    Recent steroid use does not establish stability.

  • C. Rapidly progressive disease

    Progressive disease predicts graft failure.

  • D. Active segmental inflammation

    Active inflammation destroys transplanted melanocytes.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Dermatology question

What is the answer to this Dermatology question?

The best answer is A, Stable disease with no new lesions or Koebner phenomenon for at least 6 to 12 months. Surgical procedures such as suction blister grafting or cellular grafting succeed only in stable vitiligo, since active disease and Koebner phenomenon would depigment the graft and donor sites.

Why is "Recent use of oral steroid minipulse" not the answer?

Recent steroid use does not establish stability.

Why is "Rapidly progressive disease" not the answer?

Progressive disease predicts graft failure.

Why is "Active segmental inflammation" not the answer?

Active inflammation destroys transplanted melanocytes.

What concept does this question test?

It tests Pigmentary disorders: vitiligo surgery in Dermatology. Segmental vitiligo has the best outcomes.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Pigmentary disorders: vitiligo surgery?

Learn each condition by its primary lesion, site and signature sign. Then use the flashcards and the other Dermatology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.