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ENT · Nose: rhinoscleroma
Sample itemBiopsy of a hard, woody nasal mass shows foamy macrophages containing bacilli (Mikulicz cells) and Russell bodies. Which organism is responsible?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Klebsiella rhinoscleromatis
Rhinoscleroma is a chronic granulomatous disease caused by Klebsiella rhinoscleromatis with catarrhal, granulomatous and sclerotic stages. Mikulicz cells and Russell bodies are characteristic. Long-term streptomycin or tetracyclines are used.
Option by option
A. Rhinosporidium seeberi
Rhinosporidium produces sporangia.
B. Treponema pallidum
Syphilis shows plasma-cell infiltrate and gummas.
C. Mycobacterium leprae
Leprosy shows acid-fast bacilli in foamy cells but not Mikulicz cells or Russell bodies.
D. Klebsiella rhinoscleromatis (correct)
Correct. Mikulicz cells with Klebsiella rhinoscleromatis define the disease.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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