Nose: Samter's triad: practice question

A ENT question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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ENT · Nose: Samter's triad

Sample item

A patient with asthma and nasal polyps has bronchospasm after taking aspirin. Which advice is correct?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Avoid aspirin and other COX-1 inhibiting NSAIDs

The triad of asthma, nasal polyposis and aspirin sensitivity (Samter's triad, or aspirin-exacerbated respiratory disease) results from altered arachidonic acid metabolism with leukotriene overproduction. NSAIDs that inhibit COX-1 must be avoided.

Option by option

  • A. Avoid aspirin and other COX-1 inhibiting NSAIDs (correct)

    Correct. COX-1 NSAIDs trigger reactions and should be avoided.

  • B. Use beta-blockers

    Beta-blockers can worsen bronchospasm.

  • C. Switch to higher-dose aspirin

    Higher aspirin doses can worsen reactions outside supervised desensitisation.

  • D. Stop inhaled steroids

    Inhaled steroids are beneficial.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More ENT questions

Questions about this ENT question

What is the answer to this ENT question?

The best answer is A, Avoid aspirin and other COX-1 inhibiting NSAIDs. The triad of asthma, nasal polyposis and aspirin sensitivity (Samter's triad, or aspirin-exacerbated respiratory disease) results from altered arachidonic acid metabolism with leukotriene overproduction.

Why is "Use beta-blockers" not the answer?

Beta-blockers can worsen bronchospasm.

Why is "Switch to higher-dose aspirin" not the answer?

Higher aspirin doses can worsen reactions outside supervised desensitisation.

Why is "Stop inhaled steroids" not the answer?

Inhaled steroids are beneficial.

What concept does this question test?

It tests Nose: Samter's triad in ENT. NSAIDs that inhibit COX-1 must be avoided.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Nose: Samter's triad?

Learn tuning fork results and audiogram patterns by sketching them. Then use the flashcards and the other ENT questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.