Gestational trophoblastic disease: partial mole: practice question

A OBG question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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OBG · Gestational trophoblastic disease: partial mole

Sample item

Which feature favours a partial hydatidiform mole over a complete mole?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Presence of fetal parts and focal villous swelling with triploidy

A partial mole has a triploid karyotype, some normal villi, an identifiable fetus or fetal tissue and lower hCG levels. Large-for-date uterus, theca lutein cysts and very high hCG are typical of a complete mole. Risk of malignant change is lower (under 5 per cent).

Option by option

  • A. Uterus larger than gestational age

    A large-for-date uterus is more typical of complete mole.

  • B. Very high hCG above 100,000 mIU/mL

    Very high hCG is typical of complete mole.

  • C. Large theca lutein cysts

    Theca lutein cysts accompany high hCG states.

  • D. Presence of fetal parts and focal villous swelling with triploidy (correct)

    Correct. Fetal parts and triploidy characterise partial mole.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this OBG question

What is the answer to this OBG question?

The best answer is D, Presence of fetal parts and focal villous swelling with triploidy. A partial mole has a triploid karyotype, some normal villi, an identifiable fetus or fetal tissue and lower hCG levels.

Why is "Uterus larger than gestational age" not the answer?

A large-for-date uterus is more typical of complete mole.

Why is "Very high hCG above 100,000 mIU/mL" not the answer?

Very high hCG is typical of complete mole.

Why is "Large theca lutein cysts" not the answer?

Theca lutein cysts accompany high hCG states.

What concept does this question test?

It tests Gestational trophoblastic disease: partial mole in OBG. Large-for-date uterus, theca lutein cysts and very high hCG are typical of a complete mole. Risk of malignant change is lower (under 5 per cent).

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Gestational trophoblastic disease: partial mole?

Learn management algorithms as steps: PPH, eclampsia, ectopic pregnancy. Then use the flashcards and the other OBG questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.