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OBG · Congenital infections: varicella
Sample itemA non-immune pregnant woman at 24 weeks is exposed to chickenpox 4 days ago. What is the appropriate action?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Varicella zoster immunoglobulin within 10 days of exposure
Non-immune pregnant women exposed to varicella should receive VZIG as soon as possible and within 10 days. Oral acyclovir is given if the rash develops, especially in pregnancy after 20 weeks. Live vaccine is contraindicated in pregnancy.
Option by option
A. No action is possible
Post-exposure prophylaxis is available.
B. Termination of pregnancy
Termination is not required.
C. Live varicella vaccine
Live vaccine is contraindicated.
D. Varicella zoster immunoglobulin within 10 days of exposure (correct)
Correct. VZIG protects against severe maternal varicella.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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