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OBG · Hypertensive disorders: antihypertensives
Sample itemWhich antihypertensive is contraindicated in pregnancy?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Enalapril
ACE inhibitors and angiotensin receptor blockers cause fetal renal damage and are contraindicated. Labetalol, nifedipine and methyldopa are the standard drugs. Hydralazine IV is used in emergencies.
Option by option
A. Methyldopa
Methyldopa is a safe, long-used drug.
B. Nifedipine
Nifedipine is first-line.
C. Labetalol
Labetalol is first-line.
D. Enalapril (correct)
Correct. ACE inhibitors are fetotoxic.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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