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OBG · Hypertensive disorders: acute severe hypertension
Sample itemWhich regimen is appropriate for acute severe hypertension in pre-eclampsia?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. IV labetalol or oral immediate-release nifedipine
IV labetalol (20 mg increasing to 80 mg), oral immediate-release nifedipine 10 mg or IV hydralazine are first-line to bring BP below 160/110 in a controlled manner. Sodium nitroprusside is reserved for refractory cases due to fetal cyanide risk.
Option by option
A. Sodium nitroprusside as the first choice
Nitroprusside carries a risk of fetal cyanide toxicity.
B. Sublingual nifedipine in all cases without monitoring
Sublingual use risks abrupt hypotension and fetal distress.
C. Enalapril
Enalapril is contraindicated.
D. IV labetalol or oral immediate-release nifedipine (correct)
Correct. These are the first-line options.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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