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OBG · Postpartum haemorrhage: community prevention
Sample itemWhere oxytocin injection is unavailable at a home birth, what is the recommended dose of misoprostol for prevention of PPH by a trained health worker?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. 600 mcg orally immediately after birth
WHO and Indian guidelines advise a single oral dose of 600 mcg misoprostol when oxytocin cannot be used, after exclusion of a second twin. Misoprostol is stable at room temperature. Side effects include shivering and fever.
Option by option
A. 50 mcg orally
50 mcg is far too low.
B. 600 mcg orally immediately after birth (correct)
Correct. 600 mcg orally is the standard preventive dose.
C. 100 mcg sublingual
100 mcg is too low.
D. 1 g rectal after one hour
1 g rectal is the dose used for treatment of atony in hospital.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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