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OBG · Postpartum haemorrhage: tranexamic acid
Sample itemTranexamic acid should be given for the treatment of PPH:
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. 1 g IV as soon as possible and within 3 hours of birth
In the WOMAN trial, tranexamic acid 1 g IV given within 3 hours of delivery reduced death due to bleeding. A second dose is given if bleeding continues after 30 minutes. It is given in addition to usual care, regardless of the cause.
Option by option
A. 10 g IV after 24 hours
Late and very high doses are inappropriate.
B. 1 g IV as soon as possible and within 3 hours of birth (correct)
Correct. Early IV tranexamic acid reduces mortality.
C. Only in non-atonic bleeding
It is used for all causes of PPH.
D. Orally after 6 hours
Oral dosing delays effect.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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