Try it
OBG · Menopause: postmenopausal bleeding
Sample itemIn a woman with postmenopausal bleeding, what is the first-line investigation?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Transvaginal ultrasound for endometrial thickness, followed by endometrial sampling
Postmenopausal bleeding needs exclusion of endometrial cancer, which occurs in about 10 per cent. An endometrial thickness of 4 mm or less has a very low risk. If it is thicker or bleeding recurs, endometrial biopsy or hysteroscopy is done.
Option by option
A. Pap smear alone
A Pap smear screens the cervix and does not assess the endometrium.
B. Hormone assay
Hormone assays do not diagnose cancer.
C. Observation for 6 months
Waiting delays diagnosis.
D. Transvaginal ultrasound for endometrial thickness, followed by endometrial sampling (correct)
Correct. TVS followed by biopsy is the standard pathway.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
More OBG questions
- Antenatal careA woman's last menstrual period began on 10 January 2026. Using Naegele's rule, what is…
- Obstetric drugsCarboprost (15-methyl PGF2α) is contraindicated in which condition?
- Hypertensive disorders of pregnancyA primigravida at 34 weeks has a blood pressure of 150/100 mmHg on two occasions and 2+…
- Obstetric immunologyAn Rh-negative mother delivers an Rh-positive baby. When should anti-D immunoglobulin be…