Gynaecological oncology: endometrial hyperplasia: practice question

A OBG question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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OBG · Gynaecological oncology: endometrial hyperplasia

Sample item

Which type of endometrial hyperplasia has the highest risk of progression to carcinoma?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Atypical hyperplasia (endometrial intraepithelial neoplasia)

Atypical hyperplasia progresses to cancer in about 25 to 30 per cent, and coexisting cancer is found in up to 40 per cent at hysterectomy. Hysterectomy is advised in women who have completed childbearing. LNG-IUS is an option for fertility-sparing treatment.

Option by option

  • A. Proliferative endometrium

    Proliferative endometrium is normal.

  • B. Complex hyperplasia without atypia

    Complex hyperplasia without atypia has about 3 per cent progression.

  • C. Simple hyperplasia without atypia

    Simple hyperplasia has about 1 per cent progression.

  • D. Atypical hyperplasia (endometrial intraepithelial neoplasia) (correct)

    Correct. Cytological atypia raises the risk markedly.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More OBG questions

Questions about this OBG question

What is the answer to this OBG question?

The best answer is D, Atypical hyperplasia (endometrial intraepithelial neoplasia). Atypical hyperplasia progresses to cancer in about 25 to 30 per cent, and coexisting cancer is found in up to 40 per cent at hysterectomy.

Why is "Proliferative endometrium" not the answer?

Proliferative endometrium is normal.

Why is "Complex hyperplasia without atypia" not the answer?

Complex hyperplasia without atypia has about 3 per cent progression.

Why is "Simple hyperplasia without atypia" not the answer?

Simple hyperplasia has about 1 per cent progression.

What concept does this question test?

It tests Gynaecological oncology: endometrial hyperplasia in OBG. Hysterectomy is advised in women who have completed childbearing. LNG-IUS is an option for fertility-sparing treatment.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Gynaecological oncology: endometrial hyperplasia?

Learn management algorithms as steps: PPH, eclampsia, ectopic pregnancy. Then use the flashcards and the other OBG questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.