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OBG · Gynaecological oncology: cervical intraepithelial neoplasia
Sample itemA woman has CIN 3 confined to the ectocervix on colposcopic biopsy, with the entire lesion visible. What is the appropriate treatment?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Excision by LEEP or cold knife conisation
High-grade CIN is treated by excision (LEEP, cold knife conisation) or ablation when the lesion is entirely visible and no invasive disease is suspected. Hysterectomy is not needed for CIN. Follow-up is by cytology or HPV test at 6 to 12 months.
Option by option
A. Radical hysterectomy
Radical hysterectomy is for invasive cancer.
B. Excision by LEEP or cold knife conisation (correct)
Correct. Excision gives treatment and histological assessment.
C. Observation for one year
CIN 3 requires treatment, not observation.
D. Chemoradiation
Chemoradiation is for advanced cancer.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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