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Ophthalmology · Cornea: transparency
Sample itemWhich mechanism is chiefly responsible for keeping the normal cornea clear?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Relative dehydration maintained by the endothelial pump
The stroma stays relatively dehydrated because the endothelium pumps fluid out using Na-K ATPase, and because collagen fibrils are regularly arranged. Endothelial failure produces stromal oedema and haze.
Option by option
A. Thick Bowman's layer that scatters no light
Bowman's layer does not control clarity and does not regenerate.
B. High water content of the epithelium
Epithelium acts as a barrier and does not drive deturgescence.
C. Abundant blood vessels supplying the stroma
The normal cornea is avascular, and vessels would reduce clarity.
D. Relative dehydration maintained by the endothelial pump (correct)
Correct. Endothelial pump function keeps the stroma at about 78 percent water and transparent.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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