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Ophthalmology · Cornea: layers
Sample itemAfter a deep corneal injury, which layer is secreted by the endothelium and can regenerate?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Descemet's membrane
Descemet's membrane is the basement membrane of the endothelium and can be re-laid after injury. Bowman's layer and the stroma heal by scarring, while the epithelium regenerates from limbal stem cells.
Option by option
A. Descemet's membrane (correct)
Correct. It is the endothelial basement membrane and it regenerates.
B. Bowman's layer
Bowman's layer does not regenerate and heals with scar.
C. Corneal epithelium
The epithelium regenerates from limbal stem cells and is not secreted by the endothelium.
D. Corneal stroma
The stroma repairs with fibrous scar tissue, not true regeneration.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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