Uveitis: VKH syndrome: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Uveitis: VKH syndrome

Sample item

A young Asian woman has bilateral serous retinal detachments, headache, tinnitus and later poliosis and vitiligo. What is the diagnosis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Vogt-Koyanagi-Harada disease

VKH is an autoimmune attack on melanocytes with meningism, uveitis and later sunset-glow fundus, with poliosis, vitiligo and alopecia. High-dose steroids then immunosuppressants are used.

Option by option

  • A. Vogt-Koyanagi-Harada disease (correct)

    Correct. Multisystem melanocyte involvement is classic.

  • B. Behcet disease

    Behcet has oral ulcers and hypopyon uveitis.

  • C. Toxoplasmosis

    Toxoplasmosis gives a focal retinochoroiditis.

  • D. Sarcoidosis

    Sarcoidosis has granulomas and hilar nodes.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Ophthalmology questions

Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is A, Vogt-Koyanagi-Harada disease. VKH is an autoimmune attack on melanocytes with meningism, uveitis and later sunset-glow fundus, with poliosis, vitiligo and alopecia.

Why is "Behcet disease" not the answer?

Behcet has oral ulcers and hypopyon uveitis.

Why is "Toxoplasmosis" not the answer?

Toxoplasmosis gives a focal retinochoroiditis.

Why is "Sarcoidosis" not the answer?

Sarcoidosis has granulomas and hilar nodes.

What concept does this question test?

It tests Uveitis: VKH syndrome in Ophthalmology. High-dose steroids then immunosuppressants are used.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Uveitis: VKH syndrome?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.