Uveitis: Behcet disease: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Uveitis: Behcet disease

Sample item

A young man from the Silk Route region has recurrent oral ulcers, genital ulcers and hypopyon uveitis without redness. Which HLA is associated?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. HLA-B51

Behcet disease is a vasculitis with recurrent oral aphthae, genital ulcers and relapsing uveitis with a hypopyon that is classically non-red. HLA-B51 is the genetic association.

Option by option

  • A. HLA-DR3

    HLA-DR3 is not the Behcet association.

  • B. HLA-B51 (correct)

    Correct. HLA-B51 is linked to Behcet disease.

  • C. HLA-B27

    HLA-B27 is linked to spondyloarthropathies.

  • D. HLA-A29

    HLA-A29 is linked to birdshot chorioretinopathy.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Ophthalmology questions

Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is B, HLA-B51. Behcet disease is a vasculitis with recurrent oral aphthae, genital ulcers and relapsing uveitis with a hypopyon that is classically non-red.

Why is "HLA-DR3" not the answer?

HLA-DR3 is not the Behcet association.

Why is "HLA-B27" not the answer?

HLA-B27 is linked to spondyloarthropathies.

Why is "HLA-A29" not the answer?

HLA-A29 is linked to birdshot chorioretinopathy.

What concept does this question test?

It tests Uveitis: Behcet disease in Ophthalmology. HLA-B51 is the genetic association.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Uveitis: Behcet disease?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.