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Ophthalmology · Uvea: choroidal melanoma
Sample itemA 55-year-old has a dome-shaped pigmented subretinal mass that breaks through Bruch's membrane into a mushroom shape. What is the commonest site of metastasis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Liver
Uveal melanoma is the commonest primary intraocular malignancy in adults and spreads haematogenously, mainly to the liver. Plaque brachytherapy is used for small to medium tumours.
Option by option
A. Bone
Bone metastasis is less common.
B. Lung
Lung is less common.
C. Brain
Brain metastasis is less common.
D. Liver (correct)
Correct. Hepatic metastasis is the rule.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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