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Orthopaedics · Bone tumours: adamantinoma
Sample itemA young adult has a slowly growing, multilocular lytic lesion in the anterior cortex of the mid-tibial diaphysis. What is the most likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Adamantinoma
Adamantinoma is a rare low-grade malignant tumour occurring almost exclusively in the tibial diaphysis, with epithelial islands in a fibrous stroma. It is related to osteofibrous dysplasia and treated with wide resection.
Option by option
A. Chordoma
Chordoma arises in the sacrum or clivus.
B. Giant cell tumour
Giant cell tumour is epiphyseal.
C. Osteosarcoma
Osteosarcoma is typically metaphyseal and more aggressive.
D. Adamantinoma (correct)
Correct. A cortical tibial diaphyseal lesion is typical of adamantinoma.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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