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Psychiatry · Antidepressants: trazodone
Sample itemAn antidepressant with strong sedation used for insomnia, which can cause a prolonged painful erection in men, is:
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Trazodone
Trazodone blocks 5-HT2A and alpha-1 receptors, producing sedation and orthostasis, and priapism is a rare, serious effect that requires urgent attention. It is often used at low doses as a hypnotic.
Option by option
A. Imipramine
Imipramine can cause urinary retention and arrhythmias.
B. Trazodone (correct)
Correct. Priapism is characteristic of trazodone (alpha-1 blockade).
C. Sertraline
Sertraline more commonly causes delayed ejaculation.
D. Moclobemide
Moclobemide is a reversible MAO-A inhibitor.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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