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Radiology · MRI: contrast agent
Sample itemGadolinium chelates enhance MR images mainly by which mechanism?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Paramagnetic effect that shortens T1 relaxation time
Gadolinium is paramagnetic and shortens T1 of nearby water protons, so enhancing tissue turns bright on T1 images. It does not attenuate X-rays like iodine. In severe renal failure, linear agents carry a risk of nephrogenic systemic fibrosis.
Option by option
A. Absorbing X-rays
X-ray attenuation is the principle of iodinated contrast.
B. Emitting positrons
Positron emission is the principle of PET tracers.
C. Paramagnetic effect that shortens T1 relaxation time (correct)
Correct. T1 shortening produces signal increase.
D. Increasing proton density in tissue
Gadolinium does not change proton density.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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