Contrast: prevention of nephropathy: practice question

A Radiology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Radiology · Contrast: prevention of nephropathy

Sample item

Which measure is the most effective for reducing the risk of contrast-induced nephropathy in an at-risk patient?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Intravenous hydration with saline before and after contrast

Adequate hydration with isotonic fluid is the best proven preventive strategy. Using the lowest dose of iso- or low-osmolar contrast and stopping nephrotoxic drugs also helps. Diuretics can worsen volume depletion.

Option by option

  • A. Diuretic loading with furosemide

    Furosemide may cause volume depletion and increase risk.

  • B. Fasting for 24 hours

    Fasting does not protect the kidney and may cause dehydration.

  • C. High-osmolar contrast to improve imaging

    High-osmolar agents are more nephrotoxic.

  • D. Intravenous hydration with saline before and after contrast (correct)

    Correct. Volume expansion reduces renal injury.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Radiology question

What is the answer to this Radiology question?

The best answer is D, Intravenous hydration with saline before and after contrast. Adequate hydration with isotonic fluid is the best proven preventive strategy.

Why is "Diuretic loading with furosemide" not the answer?

Furosemide may cause volume depletion and increase risk.

Why is "Fasting for 24 hours" not the answer?

Fasting does not protect the kidney and may cause dehydration.

Why is "High-osmolar contrast to improve imaging" not the answer?

High-osmolar agents are more nephrotoxic.

What concept does this question test?

It tests Contrast: prevention of nephropathy in Radiology. Using the lowest dose of iso- or low-osmolar contrast and stopping nephrotoxic drugs also helps. Diuretics can worsen volume depletion.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Contrast: prevention of nephropathy?

Learn signs with the image, and the disease they point to. Then use the flashcards and the other Radiology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.