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Radiology · Chest imaging: pulmonary arteriovenous malformation
Sample itemA patient with recurrent epistaxis and a family history of the same has a chest CT showing a well-defined lobulated nodule with a feeding artery and draining vein. What is the likely underlying diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Hereditary haemorrhagic telangiectasia with pulmonary AVM
Pulmonary AVMs are strongly associated with hereditary haemorrhagic telangiectasia (Osler-Weber-Rendu) and may cause hypoxaemia, paradoxical emboli and brain abscess. Contrast-enhanced CT shows the feeding vessel. Embolisation is the treatment.
Option by option
A. Silicosis
Silicosis forms nodules without vessels.
B. Sarcoidosis
Sarcoidosis causes nodes and perilymphatic nodules.
C. Cystic fibrosis
Cystic fibrosis causes bronchiectasis.
D. Hereditary haemorrhagic telangiectasia with pulmonary AVM (correct)
Correct. Epistaxis with a pulmonary AVM suggests HHT.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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