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Radiology · Liver imaging: focal nodular hyperplasia
Sample itemA young woman has an incidental liver lesion that is isodense on non-contrast CT, enhances intensely in the arterial phase and has a central stellate scar that enhances in the delayed phase. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Focal nodular hyperplasia
FNH is a benign hyperplastic lesion with a central scar, usually asymptomatic and needing no treatment. Hepatic adenomas are linked to oral contraceptive use and carry a risk of haemorrhage. A fibrolamellar carcinoma has a central scar that is typically hypointense on T2.
Option by option
A. Focal nodular hyperplasia (correct)
Correct. Homogeneous arterial enhancement with a central scar suggests FNH.
B. Hepatic adenoma
Adenomas are heterogeneous, linked with OCP use and tend to bleed.
C. Hydatid cyst
A hydatid cyst shows daughter cysts and a calcified wall.
D. Fibrolamellar carcinoma
Fibrolamellar carcinoma is large with a scar that is dark on T2 and occurs without cirrhosis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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