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Radiology · Nuclear medicine: cold thyroid nodule
Sample itemA thyroid scan shows a solitary nodule that does not take up the tracer (cold nodule) in a euthyroid patient. What is the best next step?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Ultrasound-guided fine needle aspiration cytology
About 5 to 10 percent of cold nodules are malignant, and evaluation is with ultrasound and fine needle aspiration. Hot nodules are almost always benign. Radioiodine or antithyroid drugs are used for hyperfunctioning nodules.
Option by option
A. Ultrasound-guided fine needle aspiration cytology (correct)
Correct. A cold nodule needs cytology.
B. Observation without any test
Observation alone is inappropriate for a suspicious nodule.
C. Start antithyroid drugs
The patient is euthyroid, so antithyroid drugs are not needed.
D. Immediate radioiodine therapy
Radioiodine therapy is for hot nodules.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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