Haematology: haemophilia A management: practice question

A General Medicine question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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General Medicine · Haematology: haemophilia A management

Sample item

A boy with known severe haemophilia A develops an acutely painful swollen knee after minor trauma. What is the most appropriate treatment?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Factor VIII concentrate

Haemophilia A is an X-linked factor VIII deficiency with prolonged aPTT and normal PT, platelet count and bleeding time. Acute haemarthrosis needs prompt factor VIII replacement along with rest, ice, compression and elevation. Aspirin and NSAIDs are avoided.

Option by option

  • A. Factor VIII concentrate (correct)

    Correct. Factor VIII replacement is specific treatment for haemarthrosis.

  • B. Platelet transfusion

    Platelets are normal in haemophilia and would not correct the defect.

  • C. Vitamin K injection

    Vitamin K corrects deficiency of factors II, VII, IX and X, not factor VIII.

  • D. Aspirin for pain

    Aspirin impairs platelet function and aggravates bleeding.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More General Medicine questions

Questions about this General Medicine question

What is the answer to this General Medicine question?

The best answer is A, Factor VIII concentrate. Haemophilia A is an X-linked factor VIII deficiency with prolonged aPTT and normal PT, platelet count and bleeding time.

Why is "Platelet transfusion" not the answer?

Platelets are normal in haemophilia and would not correct the defect.

Why is "Vitamin K injection" not the answer?

Vitamin K corrects deficiency of factors II, VII, IX and X, not factor VIII.

Why is "Aspirin for pain" not the answer?

Aspirin impairs platelet function and aggravates bleeding.

What concept does this question test?

It tests Haematology: haemophilia A management in General Medicine. Acute haemarthrosis needs prompt factor VIII replacement along with rest, ice, compression and elevation. Aspirin and NSAIDs are avoided.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Haematology: haemophilia A management?

For each disease know the classic presentation, the best test, and the first-line treatment. Then use the flashcards and the other General Medicine questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.