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General Medicine · Cardiology: ventricular septal defect
Sample itemA 6-year-old child has a loud harsh pansystolic murmur at the left lower sternal border with a palpable thrill. The pulmonary second sound is normal. What is the most likely lesion?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Ventricular septal defect
A small restrictive VSD produces a loud harsh pansystolic murmur with a thrill at the left lower sternal border. The loudness reflects a high pressure gradient across a small hole. Large defects have softer murmurs and may lead to pulmonary hypertension.
Option by option
A. Atrial septal defect
ASD causes an ejection systolic pulmonary flow murmur and a fixed split second sound.
B. Ventricular septal defect (correct)
Correct. A pansystolic murmur with thrill at the left lower sternal border is typical of a small VSD.
C. Patent ductus arteriosus
PDA produces a continuous machinery murmur below the left clavicle.
D. Pulmonary stenosis
Pulmonary stenosis gives an ejection systolic murmur at the upper left sternal border, often with an ejection click.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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