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General Medicine · Cardiology: acute viral myocarditis
Sample itemA 22-year-old man has chest pain and dyspnoea a week after a flu-like illness. The ECG shows diffuse ST elevation, troponin is raised and coronary angiography is normal. Which agent is the most common cause?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Coxsackievirus B
Viral infection, especially with enteroviruses such as coxsackievirus B, is the commonest cause of myocarditis in developed and developing regions alike. The presentation can mimic myocardial infarction with normal coronaries, and cardiac MRI shows patchy late gadolinium enhancement. Treatment is supportive with standard heart failure therapy.
Option by option
A. Trypanosoma cruzi
T. cruzi causes Chagas myocarditis, which is confined to endemic regions of the Americas.
B. Corynebacterium diphtheriae
Diphtheria toxin can cause myocarditis but is much less common.
C. Coxsackievirus B (correct)
Correct. Enteroviruses, particularly coxsackie B, are the leading cause.
D. Systemic lupus erythematosus
Lupus can cause myocarditis but is not the usual cause in a young man after a flu-like illness.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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