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General Medicine · Rheumatology: Kawasaki disease
Sample itemA 3-year-old has six days of fever, non-exudative conjunctival injection, red cracked lips, a cervical lymph node, a rash and peeling of the fingertips. Which treatment reduces the risk of coronary aneurysm?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Intravenous immunoglobulin with aspirin
Kawasaki disease is a medium-vessel vasculitis of young children with prolonged fever and mucocutaneous features. Intravenous immunoglobulin given within 10 days, with aspirin, markedly reduces coronary artery aneurysms. Echocardiography is needed at diagnosis and follow-up.
Option by option
A. Corticosteroids alone
Steroids alone are not the standard first-line therapy.
B. Intravenous immunoglobulin with aspirin (correct)
Correct. IVIG with aspirin is the standard therapy.
C. Oral penicillin
Penicillin treats streptococcal disease, which does not explain the presentation.
D. Intravenous acyclovir
Acyclovir treats herpes virus infections.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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