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General Medicine · Emergency medicine: scorpion sting
Sample itemA child stung by a red scorpion in rural Maharashtra develops profuse sweating, hypertension, tachycardia, priapism and early pulmonary oedema. Which drug is the treatment of choice?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Prazosin
Mesobuthus tamulus venom causes an autonomic storm from sodium channel effects, producing massive catecholamine release with hypertension, pulmonary oedema and myocarditis. The alpha-blocker prazosin counteracts the vasoconstriction and improves outcome. Beta-blockers worsen pulmonary oedema by unopposed alpha effects, and atropine and adrenaline are unhelpful.
Option by option
A. Atropine
Atropine adds to the tachycardia and does not treat the catecholamine surge.
B. Adrenaline
Adrenaline would aggravate hypertension and pulmonary oedema.
C. Propranolol
Propranolol can precipitate worse cardiac failure and is avoided.
D. Prazosin (correct)
Correct. Prazosin antagonises the alpha-adrenergic effects of the envenomation.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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