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General Surgery · Urology: schistosomal bladder cancer
Sample itemA farmer from an area endemic for Schistosoma haematobium has painless haematuria and a bladder tumour. Which histological type is typical in this setting?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Squamous cell carcinoma
Chronic urinary schistosomiasis causes squamous metaplasia and carcinoma of the bladder. In non-endemic areas the commonest type is transitional cell (urothelial) carcinoma, associated with smoking and aromatic amines. Treatment depends on invasion depth.
Option by option
A. Small cell carcinoma
Small cell carcinoma is rare.
B. Transitional cell carcinoma
Transitional cell is the usual type elsewhere.
C. Squamous cell carcinoma (correct)
Correct. Squamous carcinoma is linked to S. haematobium.
D. Adenocarcinoma
Adenocarcinoma is rare and associated with urachal remnants.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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