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General Medicine · Gastroenterology
Sample itemFever, jaundice and right upper quadrant pain together (Charcot's triad) suggest:
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Ascending cholangitis
Charcot's triad indicates infected obstructed bile ducts, usually from a common bile duct stone. Adding hypotension and confusion makes Reynolds' pentad. Treatment is antibiotics and urgent biliary drainage by ERCP.
Option by option
A. Ascending cholangitis (correct)
Correct. Infected, obstructed bile ducts give fever, jaundice and pain.
B. Acute cholecystitis
Cholecystitis gives pain and fever but rarely jaundice.
C. Acute hepatitis A
Hepatitis A gives jaundice with prodromal illness and raised transaminases, usually without marked pain.
D. Acute pancreatitis
Pancreatitis presents with epigastric pain radiating to the back and raised lipase.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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